Quantitative Determination of Thiol Status of Proteins and Cells by Nitroxyl Biradical .RS-SR

Quantitative Determination of Thiol Status of Proteins and Cells by Nitroxyl Biradical

Suppression of spin-spin coupling in nitroxyl biradicals by supramolecular host-guest interactions.

The use of supramolecular architectures to control the spatially dependent spin exchange (spin communication) between two covalently linked radical centers (biradical) has been explored. Cucurbit[8]uril, through supramolecular steric effect, completely suppresses spin exchange between two adjacent radical centers in a biradical.

Transportin-SR, a Nuclear Import Receptor for SR Proteins

The SR proteins, a group of abundant arginine/serine (RS)-rich proteins, are essential pre-mRNA splicing factors that are localized in the nucleus. The RS domain of these proteins serves as a nuclear localization signal. We found that RS domain-bearing proteins do not utilize any of the known nuclear import receptors and identified a novel nuclear import receptor specific for SR proteins. The S...

Replacement of threonine-55 with glycine decreases the reduction rate of OsTrx20 by glutathione

Thioredoxins (Trxs) are small ubiquitous oxidoreductase proteins with two redox-active Cys residues in a conserved active site (WCG/PPC) that regulate numerous target proteins via thiol/disulfide exchanges in the cells of prokaryotes and eukaryotes. The isoforms OsTrx23 with a typical active site (WCGPC) and OsTrx20 with an atypical active site (WCTPC) are two  Trx h- type isoforms in rice that ...

P-2: Study The Effect of Oral Zinc Supplementation on Thiol Oxido-Reductive Index in Spermatozoa of Patients with Asthenospermia

Background: There are several causes leading to male infertility, like oxidative stress, and nutritional deficiency of trace elements i.e., selenium and zinc. The Zinc is the following only to iron as the most abundant element in the body. Although, Zinc is found in red meat, white meat, fish, and milk; the World Health Organization (WHO) approximates that one-third of world population is defic...